Wytheville Community College is approved by the State Board for Community Colleges and by the Virginia Community College System. The associate degree curricula of the college have also been approved by the State Council of Higher Education for Virginia.

Wytheville Community College is accredited by the Southern Association of Colleges and Schools Commission on Colleges (SACSCOC) to award the associate degree. Wytheville Community College also may offer credentials such as certificates and diplomas at approved degree levels. Questions about the accreditation of Wytheville Community College may be directed in writing to the Southern Association of Colleges and Schools Commission on Colleges at 1866 Southern Lane, Decatur, GA 30033-4097, by calling (404) 679-4500, or by using information available on SACSCOC's website (www.sacscoc.org).

Wytheville Community College has been approved to participate in the National Council for State Authorization Reciprocity Agreements

The Associate Degree Nursing program at Wytheville Community College at the Main Campus located in Wytheville, Virginia is accredited by the:
Accreditation Commission for Education in Nursing (ACEN)
3390 Peachtree Road NE, Suite 1400 Atlanta, GA 30326 (404) 975-5000.
The most recent accreditation decision made by the ACEN Board of Commissioners for the Associate Degree Nursing program is Continuing Accreditation.

The Practical Nursing Program is approved by the Virginia State Board of Nursing, Perimeter Center, 9960 Mayland Drive, Suite 300, Henrico, Virginia 23233-1463; (804) 367-4515.

The Medical Laboratory Technology Program is accredited by the National Accrediting Agency of Clinical Laboratory Sciences (NAACLS), 5600 N. River Rd., Suite 720, Rosemont, Illinois 60018-5119; (847) 939-3597.

The Dental Hygiene program is accredited by the Commission on Dental Accreditation of the American Dental Association (ADA), 211 East Chicago Ave., Chicago, Illinois 60611-2678; (312) 440-2500.

The EMS-Paramedics Program has been granted approval by the Virginia Office of EMS and national accreditation by the Committee on Accreditation of Allied Health Educational Programs (CAAHEP), 1361 Park Street, Clearwater, Florida 33756; (727) 210-2350.

The Physical Therapist Assistant program is accredited by the Commission on Accreditation in Physical Therapy Education of the American Physical Therapy Association (CAPTE), 1111 North Fairfax Street, Alexandria, Virginia 22314-1488; (703) 684-2782.